| Tahun |
Pemenang dan nominee |
Film |
Peran |
| 2000 | Laura Linney | You Can Count on Me | Samantha "Sammy" Prescott |
| Ellen Burstyn | Requiem for a Dream | Sara Goldfarb |
| Michelle Yeoh | Crouching Tiger, Hidden Dragon | Yu Shu Lien |
| 2001 | Sissy Spacek | In the Bedroom | Ruth Fowler |
| Audrey Tautou | Amélie (Le fabuleux destin d'Amélie Poulain) | Amélie Poulain |
| Thora Birch | Ghost World | Enid |
| 2002 | Julianne Moore | Far from Heaven | Cathy Whitaker |
| Maggie Gyllenhaal | Secretary | Lee Holloway |
| Nicole Kidman | The Hours | Virginia Woolf |
| Diane Lane | Unfaithful | Constance Sumner |
| Meryl Streep | The Hours | Clarissa Vaughan |
| 2003 | Charlize Theron | Monster | Aileen Wuornos |
| Jennifer Connelly | House of Sand and Fog | Kathy Nicolo |
| Scarlett Johansson | Lost in Translation | Charlotte |
| 2004 | Imelda Staunton | Vera Drake | Vera Drake |
| Laura Linney | Kinsey | Clara McMillen |
| Hilary Swank | Million Dollar Baby | Maggie Fitzgerald |
| 2005 | Felicity Huffman | Transamerica | Stanley Schupak / Bree Osbourne |
| Laura Linney | The Squid and the Whale | Joan Berkman |
| Charlize Theron | North Country | Josey Aimes |
| Naomi Watts | King Kong | Ann Darrow |
| 2006 | Helen Mirren | The Queen | Ratu Elizabeth II |
| Judi Dench | Notes on a Scandal | Barbara Covett |
| Kate Winslet | Little Children | Sarah Pierce |
| 2007 | Marion Cotillard | La Vie en Rose (La môme) | Édith Piaf |
| Anamaria Marinca | 4 Months, 3 Weeks and 2 Days | Otilia Mihartescu |
| Ellen Page | Juno | Juno MacGuff |
| 2008 | Kate Winslet | The Reader | Hanna Schmitz |
| Revolutionary Road | April Wheeler |
| Sally Hawkins | Happy-Go-Lucky | Pauline "Poppy" Cross |
| Meryl Streep | Doubt | Sister Aloysius Beauvier |
| 2009 | Carey Mulligan | An Education | Jenny Miller |
| Gabourey Sidibe | Precious | Claireece Precious Jones |
| Meryl Streep | Julie & Julia | Julia Child |