He commanded the IRGC South-East Quds Force Operational Base in Zahedan in Sistan and Baluchestan province from 2019 to 2022. He was linked to violent crackdowns and killings of protestors during the 2022 Mahsa Amini protests in Sistan and Baluchestan Province.[4] Karami served as the Governor of Sistan and Baluchestan province in the Government of Ebrahim Raisi from 2022 to 2024.[5][6][7] He has also served as the Commander of the Guards Officer of Imam Hossein University, which is affiliated with the IRGC, since 2024.
Canada: In 2021, one month after the start of the Mahsa Amini protests in Iran, the Canadian government sanctioned Karami on charges of "gross human rights violations." Previously, the United States had placed him on its sanctions list.[9]
European Union: On 24 January 2023, the European Union issued new sanctions against the Islamic Republic of Iran, which included 18 natural and 19 legal entities of the Islamic Republic Iran, including Karami. This sanction is due to his role in the brutal suppression of protests after the Death of Mahsa Amini by the Islamic Republic.[10][11]
United Kingdom: On 20 February 2023, the British Foreign Office added the names of three judges, three members of the Revolutionary Guard Corps, and two governors, including Karami, to the sanctions list. These sanctions include asset freezes and a travel ban to the United Kingdom.[12]