Oxycodegol

Names
IUPAC name (4R,4aS,7S,7aR,12bS)-9-methoxy-7-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-4a-ol
Other names Oxicodegol; Loxicodegol; NKTR-181
Identifiers
CAS Number	1211231-76-3 N
3D model (JSmol)	Interactive image
ChemSpider	64854462
DrugBank	DB14146
IUPHAR/BPS	10652
KEGG	D11424
PubChem CID	73673720
UNII	J2WIV0JMML
InChI InChI=1S/C31H49NO10/c1-32-9-8-30-27-23-4-5-24(35-3)28(27)42-29(30)25(6-7-31(30,33)26(32)22-23)41-21-20-40-19-18-39-17-16-38-15-14-37-13-12-36-11-10-34-2/h4-5,25-26,29,33H,6-22H2,1-3H3/t25-,26+,29-,30-,31+/m0/s1 Key: RQHILGKAOIGUHU-XPLSERNMSA-N
SMILES CN1CC[C@]23[C@@H]4[C@H](CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O)OCCOCCOCCOCCOCCOCCOC
Properties
Chemical formula	C31H49NO10
Molar mass	595.730 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Oxycodegol (also known as loxicodegol and NKTR-181) is an experimental μ-opioid receptor agonist for the treatment of pain.^[1][2] It has had success for back pain as an alternative to traditional opioids,^[3] which have potential for abuse. It acts more slowly on the central nervous system, reducing risk for abuse and respiratory depression.^[1]

References

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