ENSIKLOPEDIA Cari Tekan Enter untuk memulai pencarian cepat. Kembali ke Ensiklopedia Arsip Wikipedia Indonesia Inogatran Inogatran Inogatran Names IUPAC name 2-{[(2R)-1-[(2S)-2-[(4-Carbamimidamidopropyl)carbamoyl]piperidin-1-yl]-3-cyclohexyl-1-oxopropan-2-yl]amino}acetic acid Other names N-[(1R)-2-Cyclohexyl-1-[[(2S)-2-[(3-guanidinopropyl)carbamoyl]piperidino]carbonyl]ethyl]glycine Identifiers CAS Number 155415-08-0 3D model (JSmol) Interactive image ChEMBL ChEMBL114715 ChemSpider 59397 PubChem CID 66005 UNII 428409I84L Y CompTox Dashboard (EPA) DTXSID50165895 InChI InChI=1S/C21H38N6O4/c22-21(23)25-11-6-10-24-19(30)17-9-4-5-12-27(17)20(31)16(26-14-18(28)29)13-15-7-2-1-3-8-15/h15-17,26H,1-14H2,(H,24,30)(H,28,29)(H4,22,23,25)/t16-,17+/m1/s1Key: CDPROXZBMHOBTQ-SJORKVTESA-N SMILES NC(=N)NCCCNC(=O)[C@@H]1CCCCN1C(=O)[C@@H](CC2CCCCC2)NCC(=O)O Properties Chemical formula C21H38N6O4 Molar mass 438.6 g/mol Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references Chemical compound Inogatran (INN)[1] is a low molecular weight peptidomimetic thrombin inhibitor. Inogatran was developed for the potential treatment of arterial and venous thrombotic diseases.[2] References ↑ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 35" (PDF). World Health Organization. p. 13. Retrieved 2 December 2016. ↑ Teger-Nilsson, AC; Bylund, R; Gustafsson, D; Gyzander, E; Eriksson, U (January 1997). "In Vitro Effects of Inogatran, a Selective Low Molecular Weight Thrombin Inhibitor". Thrombosis Research. 85 (2): 133–45. doi:10.1016/s0049-3848(96)00230-7. PMID 9058487. vteAntithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)Antiplatelet drugsGlycoprotein IIb/IIIa inhibitors Abciximab Eptifibatide Orbofiban Roxifiban Sibrafiban§ Tirofiban ADP receptor/P2Y12 inhibitors Thienopyridines Clopidogrel Prasugrel Ticlopidine Nucleotide/nucleoside analogs Cangrelor Elinogrel Ticagrelor Prostaglandin analogue (PGI2) Beraprost Iloprost Prostacyclin Treprostinil COX inhibitors Acetylsalicylic acid/Aspirin# Aloxiprin Carbasalate calcium Indobufen Triflusal Thromboxane inhibitors Thromboxane synthase inhibitors Dipyridamole (+ aspirin) Picotamide Terbogrel Receptor antagonists Terbogrel Terutroban§ Phosphodiesterase inhibitors Cilostazol Dipyridamole Triflusal Other Cloricromen Ditazole Vorapaxar AnticoagulantsVitamin K antagonists(inhibit II, VII, IX, X) Coumarins: Acenocoumarol Coumatetralyl Dicoumarol Ethyl biscoumacetate Phenprocoumon Warfarin# 1,3-Indandiones: Clorindione Diphenadione Phenindione Other: Tioclomarol Factor Xa inhibitors(with some II inhibition)Heparin group/glycosaminoglycans/(bind antithrombin) Low-molecular-weight heparin Bemiparin Certoparin Dalteparin Enoxaparin Nadroparin Parnaparin Reviparin Tinzaparin Oligosaccharides Fondaparinux Idraparinux§ Heparinoids Danaparoid Dermatan sulfate Sulodexide Direct Xa inhibitors ("xabans") Apixaban Betrixaban Darexaban§ Edoxaban Otamixaban§ Rivaroxaban Direct thrombin (IIa) inhibitors Bivalent: Hirudin Bivalirudin Desirudin Lepirudin‡ Univalent: Argatroban Dabigatran Efegatran Inogatran§ Melagatran‡ Ximelagatran‡ Other Abelacimab Antithrombin III Defibrotide Fitusiran Nafamostat Protein C Drotrecogin alfa‡ Ramatroban REG1 Thrombolytic drugs/fibrinolytics Plasminogen activators: r-tPA Alteplase# Reteplase Tenecteplase Desmoteplase† UPA Saruplase Urokinase Anistreplase Monteplase Streptokinase# Other: Ancrod‡ Brinase Caplacizumab Fibrinolysin Non-medicinal Citrate Ethylenediaminetetraacetic acid (EDTA) Oxalate #WHO-EM ‡Withdrawn from market Clinical trials: †Phase III §Never to phase III This drug article relating to the blood and blood forming organs is a stub. You can help Wikipedia by adding missing information.vte
