The species has been known previously as Flexibacter columnaris, Bacillus columnaris, and Cytophaga columnaris.
Flavobacterium columnare is one of the oldest known diseases among warm-water fish, and manifests itself as an infection commonly known as columnaris. Infections are the second leading cause of mortality in pond raised catfish in the southeastern United States.[4] Early treatment with potassium permanganate has been shown to increase survival rate, although the difference was not statistically significant.[5]