Niobichthys suffixes -ichthys, Greek for "fish", onto Niobe, a figure from Greek mythology whose children were killed by Apollo causing her to turned to stone by Zeus and moved to a mountain peak, which remained eternally wet with her tears. This is a reference to the clouds surrounding Cerra La Neblina, this species' type locality. The Specific named honors the American ichthyologistCarl J. Ferraris, Jr., co-discoverer of this species when on an expedition to the Cerr La Neblina in 1984, in recognition of his work on catfish taxonomy and Neotropical ichthyology.[5]