| Name | Other names | Mechanism of action | Dosage | IOP decrease | Side effects |
| Prostaglandin analogs |
| Latanoprost | Xalatan | Increased USO (uveoscleral outflow ) | Once daily | 25-32% | pigmentation of eyelashes, eyelid skin pigmentation, hyperemia (red eye), flu-like symptoms (joint/muscle pain and headache) |
| Bimatoprost | Lumigan | Increased USO (uveoscleral outflow ) | Once daily | | blurred vision, eyelid redness, eye discomfort, permanently darken iris, darken/thicken eyelashes |
| Travoprost | Travatan | Increased USO (uveoscleral outflow ) | Once daily | | blurred vision, eyelid redness, eye discomfort, permanently darken iris, darken/thicken eyelashes |
| Beta blockers |
| Timolol | Timoptic | Decrease aqueous production | Every 12 hours | 20-30% | bronchospasm, bradycardia, depression, impotence |
| Betaxolol | Betoptic | Decrease aqueous production | Every 12 hours | 15-20% | Fewer pulmonary complications due to selective Beta blockage |
| Adrenergic agents |
| Brimonidine | Alphagan | Decrease aqueous production, increase USO | every 8–12 hours | 20-30% | blurring, foreign body sensation, eyelid edema, dryness, headache, fatigue, hypotension, depression, insomnia |
| Miotics |
| Pilocarpine | Isoptocarpine, Pilocar | Increase trabecular outflow | Every 6–12 hours | 15-25% | posterior synechia, keratitis, miosis, brow ache, cataract, myopia, retinal tear, dermatitis, increased salivation |
| Carbonic anhydrase inhibitors |
| Dorzolamide | Trusopt | Decrease aqueous production | Every 8–12 hours | 15-20% | eye irritation, bitter taste |
| Brinzolamide | Azopt | Decrease aqueous production | Every 8–12 hours | 15-20% | eye irritation, bitter taste |
| Acetazolamide | Diamox | Decrease aqueous production | Every 6–12 hours | 15-20% | malaise, depression, weight loss, kidney stones |
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