Early in his career, while studying a vitamin B12-dependent enzyme, Babior recognized that free radicals might play an important role in biologic processes.
[1] He showed that superoxide, a highly reactive oxygen derivative, was produced by white blood cellNADPH oxidase as a mechanism to kill invading bacteria. As such, Babior was able to explain the etiology of a rare genetic highly fatal immunodeficiency disease, Chronic granulomatous disease, whereby patients are unable to fight off normally non-pathogenic bacteria.
[1] Babior and others showed that the very weapons that the body makes to protect itself against microbial invasion can also play an important role in a variety of common diseases, including arthritis, arteriosclerosis, and Alzheimer's disease.[1]
Babior was married to Shirley; the couple had two children, Gregory and Jill.[1] He died in San Diego, from prostate cancer, at the age of sixty-eight.[1]