In 2021, Wheatley played sparingly in four games, earning a redshirt.[6][7] Against Auburn the following season, he recorded his first career interception.[8] In 2022, his production increased, as he totaled 27 tackles, two interceptions, and a forced fumble.[9] In 2024, Wheatley's role increased after an injury to Kevin Winston Jr..[10] At the conclusion of the regular season, he announced that he would return the following season, rather than enter the 2025 NFL draft, after totaling 77 total tackles, four pass breakups, 1.5 tackles for loss and one interception through 14 games.[11] In the 2024 Fiesta Bowl, Wheatley was named the game's defensive MVP after recording an interception and a fumble recovery, helping lead Penn State to a 31–14 victory.[12]