Kubista began his academic career in 1991 as an assistant professor in the Department of Physical Chemistry at Chalmers University of Technology.[1] From 1993 to 1997, he was an associate professor in the Department of Biochemistry at the same institution. Following this, he held the position of professor in the Department of Biochemistry at Chalmers University of Technology from 1997 to 2006.[1] He has served as head for a laboratory at the Biotechnology Institute, Czech Academy of Sciences since 2007.[5][1]
LightUp Technologies AB
In 1998 Kubista founded LightUp Technologies AB after his research finding of LightUp probes,[6] a company that develops real-time PCR tests for human infectious diseases.[7]
TATAA Biocenter
In 2001, Kubista cofounded TATAA Biocenter, and Care Equity invested in TATAA Biocenter.[8][9] To facilitate the investment, a new holding company, Bioholdings LP, was established to acquire TATAA. During restructuring connected to TATAA’s COVID-19 testing business, Kubista and his co-founders, advised by a law firm, carried out an upstream merger between two holding entities. This violated a clause in the agreement that prohibited share transfers without written consent. In June 2023, Kubista was dismissed as CEO and forfeited the founders' shares without compensation.[10] Care Equity sued Kubista.[11] As of October 2025, legal proceedings related to the merger dispute remain ongoing in the Swedish courts.[12] Kubista also sued the law firm for negligent advice and damages.[13]
Precision BioAnalytics
In 2025 Kubista together with Jens Björkman, Robert Sjöback and Fredrik Adlercreutz founded Precision BioAnalytics,[14][15] around a new preanalytical procedure that increases sensitivity and improves precision of the preanalytical process in molecular analysis.[16][17]
Studied and identified chromophores and a variety of dyes commonly used as biomolecule labels like: tryptophan, DAPI, fluorescein,[19] thiazole orange, and BEBO.[6]
Designed a probe that exhibit luminescence upon binding to specific nucleic acids.[20]
Techniques for gene expression at the level of individual cells and subcellular compartments.[21]
Discovered the Regeneration Initiating Cells (RICs) [22]
