ENSIKLOPEDIA Cari Tekan Enter untuk memulai pencarian cepat. Kembali ke Ensiklopedia Arsip Wikipedia Indonesia SDHB SDHBSDHBPengidentifikasiAliasSDHB, CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP, succinate dehydrogenase complex iron sulfur subunit B, MC2DN4ID EksternalOMIM: 185470; MGI: 1914930; HomoloGene: 2255; GeneCards: SDHB; OMA:SDHB - orthologsLokasi gen (Manusia)Kr.Kromosom 1 (manusia)[1]Pita1p36.13Awal17,018,722 pb[1]Akhir17,054,032 pb[1]Lokasi gen (Tikus)Kr.Kromosom 4 (tikus)[2]Pita4|4 D3Awal140,688,514 pb[2]Akhir140,706,504 pb[2]Pola ekspresi RNABgeeManusiaTikus (ortologi)Ekspresi tertinggi dileft ventricleapex of heartOtot gastrocnemiusmuscle of thighmucosa of transverse colonright ventricleright auricle of heartright lobe of liverOtot vastus lateralisOtot biceps brachiiEkspresi tertinggi diright ventriclemyocardium of ventricledigastric muscleinterventricular septumplantaris muscleOtot sternokleidomastoidOtot jantungsoleus muscleDiafragmacardiac muscle tissue of left ventricleReferensi data ekspresi selengkapnyaBioGPSn/aOntologi genFungsi molekuler ubiquinone binding iron-sulfur cluster binding metal ion binding succinate dehydrogenase (ubiquinone) activity Ikatan protein plasma oxidoreductase activity electron transfer activity 2 iron, 2 sulfur cluster binding 3 iron, 4 sulfur cluster binding 4 iron, 4 sulfur cluster binding Komponen seluler membran membran sel nucleoplasm mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) mitochondrial inner membrane mitokondria mitochondrial membranes respiratory chain complex II Proses biologis succinate metabolic process aerobic dissimilation Siklus asam sitrat respiratory electron transport chain Rantai transpor elektron Sumber:Amigo / QuickGOOrtologiSpesiesManusiaTikusEntrez639067680EnsemblENSG00000117118ENSMUSG00000009863UniProtP21912Q9CQA3RefSeq (mRNA)NM_003000NM_023374NM_001355515RefSeq (protein)NP_002991NP_075863NP_001342444Location (UCSC)Chr 1: 17.02 – 17.05 MbChr 4: 140.69 – 140.71 MbPubMed search[3][4]WikidataLihat/Sunting ManusiaLihat/Sunting Tikus SDHB adalah berkas genetik pada kromosom 1 lokasi 1p36.1-p35 dengan ekspresi genetik berupa protein sub-unit B dari suksinat dehidrogenase. Sub-unit B terdiri dari 3 kluster yang kaya akan sisteina. Mutasi pada gen akan menyebabkan paraganglioma dan feokromositoma, disfungsi mitokondria dan tumorigenesis.[5] Referensi 1 2 3 GRCh38: Ensembl release 89: ENSG00000117118 – Ensembl, May 2017 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000009863 – Ensembl, May 2017 ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. ↑ (Inggris) "SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-11-05. lbsOxidoreductases: CH–CH oxidoreductases (EC 1.3)1.3.1: NAD/NADP acceptor Enoyl-acyl carrier protein reductase/Enoyl ACP reductase 7-Dehydrocholesterol reductase Biliverdin reductase 2,4 Dienoyl-CoA reductase Dihydroxymethyloxo-tetrahydroquinoline dehydrogenase 1.3.3: Oxygen acceptor Dihydroorotate dehydrogenase Coproporphyrinogen III oxidase Protoporphyrinogen oxidase Bilirubin oxidase Acyl-CoA oxidase Dihydrouracil oxidase Tetrahydroberberine oxidase Secologanin synthase Tryptophan alpha,beta-oxidase Pyrroloquinoline-quinone synthase L-galactonolactone oxidase 1.3.5: Quinone Succinate dehydrogenase SDHA SDHB SDHC SDHD 1.3.99: Other acceptors Fumarate reductase Butyryl-CoA dehydrogenase Acyl CoA dehydrogenase ACADSB ACADS 5α-reductase SRD5A1 SRD5A2 SRD5A3 Glutaryl-CoA dehydrogenase Isovaleryl coenzyme A dehydrogenase 3-oxo-5beta-steroid 4-dehydrogenase Artikel bertopik gen ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.lbs
