Rosemary Carpenter Career
Starting in the 1960, Carpenter worked with Brian Harrison at the John Innes Centre on unstable mutants of the snapdragon Antirrhinum .[ 2] After meeting Carpenter during an interview at the John Innes Centre in 1983, Enrico Coen joined the center and they began a long collaboration with him using snapdragons as a model system to understand jumping genes and evolution.[ 3] [ 2] They applied a combination of molecular, genetic and morphological approaches to snapdragons with the goal of elucidating patterns in flower development[ 4] using the hundreds of Antirrhihum mutants established by Carpenter.[ 5] Carpenter retired in 2003.[ 6]
Carpenter is a plant geneticist who worked on Antirrhinum, snapdragons.
Research
Carpenter is a plant geneticist known for her research on the population genetics of the snapdragon, Antirrhihum .[ 7] [ 2] Working with Brian Harrison in the 1970s, she defined genetic instabilities in Antirrhinum and the role of temperature in controlling the rate of instability of specific genes[ 8] [ 9] and transposable elements that occur in both maize and snapdragons.[ 10] This was the first time a link between genetic instability and Antirrhihum was formalized, a milestone in research using snapdragons.[ 11] The instability of genes in snapdragons begin Carpenter's collaboration with Enrico Coen , where they first worked on transposons and the effect of temperature on the excision of specific genes[ 12] and how the transposable elements cause variability in gene expression .[ 13] [ 14] Carpenter, Coen, and their students isolated the genes controlling floral development.[ 15] [ 16] [ 17] These genetic investigations allowed them to define the patterns of color,[ 18] [ 19] shape,[ 20] [ 21] [ 22] and floral asymmetry[ 23] [ 24] in snapdragons and other plants. Carpenter's research on snapdragons includes investigations of how snapdragons select their colors using small RNA ,[ 25] which alter the selection of colors in the snapdragons.[ 26]
Selected publications
Carpenter, R; Coen, E S (1 September 1990). "Floral homeotic mutations produced by transposon-mutagenesis in Antirrhinum majus" . Genes & Development . 4 (9): 1483– 1493. doi :10.1101/gad.4.9.1483 . ISSN 0890-9369 . PMID 1979295 .
Coen, Enrico S.; Romero, JoséM.; Doyle, Sandra; Elliott, Robert; Murphy, George; Carpenter, Rosemary (1990). "floricaula: A homeotic gene required for flower development in antirrhinum majus" . Cell . 63 (6): 1311– 1322. doi :10.1016/0092-8674(90)90426-F . PMID 1702033 . S2CID 46586130 .
Carpenter, R.; Coen, E.S. (1 January 1995). "Transposon induced chimeras show that floricaula, a meristem identity gene, acts non-autonomously between cell layers" . Development . 121 (1): 19– 26. doi :10.1242/dev.121.1.19 . ISSN 0950-1991 . PMID 7867500 .
Luo, Da; Carpenter, Rosemary; Vincent, Coral; Copsey, Lucy; Coen, Enrico (1996). "Origin of floral asymmetry in Antirrhinum" . Nature . 383 (6603): 794– 799. Bibcode :1996Natur.383..794L . doi :10.1038/383794a0 . ISSN 0028-0836 . PMID 8893002 . S2CID 2188470 .
Bradley, Desmond; Carpenter, Rosemary; Copsey, Lucy; Vincent, Coral; Rothstein, Steven; Coen, Enrico (February 1996). "Control of inflorescence architecture in Antirrhinum". Nature . 379 (6568): 791– 797. Bibcode :1996Natur.379..791B . doi :10.1038/379791a0 . PMID 8587601 . S2CID 998958 .
References
↑ "Award winners: Darwin Medal" . Royal Society.
1 2 3 Coen, E. S. (1996). "Floral symmetry" . The EMBO Journal . 15 (24): 6777– 6788. doi :10.1002/j.1460-2075.1996.tb01069.x . PMC 452503 . PMID 9003753 .
↑ "Flower Development, E Coen and R Carpenter, Cell & Developmental Biology Department - JIC UK" . 20 February 2002. Archived from the original on 20 February 2002. Retrieved 25 September 2021 .
↑ "E.Coen and R.Caprpenter, Flower Development, Research Programme" . 11 March 2002. Archived from the original on 11 March 2002. Retrieved 25 September 2021 .
↑ "Return of the snapdragon" . Nature Plants . 5 (2): 121. 2019. doi :10.1038/s41477-019-0377-0 . ISSN 2055-0278 . PMID 30737515 .
↑ "Past members - Flower Development, E Coen, Cell & Developmental Biology Department - JIC UK" . rico-coen.jic.ac.uk . Archived from the original on 25 September 2021. Retrieved 25 September 2021 .
↑ Carpenter, Rosemary (1998). Studies on genetic instability in Antirrhinum majus (Thesis).
↑ Harrison, Brian J; Carpenter, Rosemary (1973). "A comparison of the instabilities at the Nivea and Pallida loci in Antirrhinum majus" . Heredity . 31 (3): 309– 323. doi :10.1038/hdy.1973.88 . ISSN 0018-067X . S2CID 21953999 .
↑ Harrison, Brian J.; Carpenter, Rosemary (1 November 1979). "Resurgence of genetic instability in Antirrhinum majus" . Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis . 63 (1): 47– 66. doi :10.1016/0027-5107(79)90103-9 . ISSN 0027-5107 .
↑ Sommer, Hans; Carpenter, Rosemary; Harrison, Brian J.; Saedler, Heinz (1985). "The transposable element Tam3 of Antirrhinum majus generates a novel type of sequence alterations upon excision" . Molecular and General Genetics . 199 (2): 225– 231. doi :10.1007/BF00330263 . ISSN 0026-8925 . S2CID 8399480 .
↑ Schwarz-Sommer, Zsuzsanna; Davies, Brendan; Hudson, Andrew (2003). "An everlasting pioneer: the story of Antirrhinum research" . Nature Reviews Genetics . 4 (8): 655– 664. doi :10.1038/nrg1127 . hdl :1842/704 . ISSN 1471-0056 . PMID 12897777 . S2CID 205482851 .
↑ Martin, Cathie; Carpenter, Rosemary; Sommer, Hans; Saedler, Heinz; Coen, Enrico S. (1985). "Molecular analysis of instability in flower pigmentation of Antirrhinum majus, following isolation of the pallida locus by transposon tagging" . The EMBO Journal . 4 (7): 1625– 1630. doi :10.1002/j.1460-2075.1985.tb03829.x . PMC 554396 . PMID 16453618 .
↑ Coen, Enrico S.; Carpenter, Rosemary; Martin, Cathie (1986). "Transposable elements generate novel spatial patterns of gene expression in antirrhinum majus" . Cell . 47 (2): 285– 296. doi :10.1016/0092-8674(86)90451-4 . PMID 3021338 . S2CID 24465394 .
↑ Carpenter, Rosemary; Martin, Cathie; Coen, Enrico S. (1987). "Comparison of genetic behaviour of the transposable element Tam3 at two unlinked pigment loci in Antirrhinum majus" . Molecular and General Genetics . 207 (1): 82– 89. doi :10.1007/BF00331494 . ISSN 0026-8925 . S2CID 31982611 .
↑ Carpenter, R; Coen, E S (1 September 1990). "Floral homeotic mutations produced by transposon-mutagenesis in Antirrhinum majus" . Genes & Development . 4 (9): 1483– 1493. doi :10.1101/gad.4.9.1483 . ISSN 0890-9369 . PMID 1979295 .
↑ Coen, Enrico S.; Romero, JoséM.; Doyle, Sandra; Elliott, Robert; Murphy, George; Carpenter, Rosemary (1990). "floricaula: A homeotic gene required for flower development in antirrhinum majus" . Cell . 63 (6): 1311– 1322. doi :10.1016/0092-8674(90)90426-F . PMID 1702033 . S2CID 46586130 .
↑ Goodrich, Justin; Carpenter, Rosemary; Coen, Enrico S. (1992). "A common gene regulates pigmentation pattern in diverse plant species" . Cell . 68 (5): 955– 964. doi :10.1016/0092-8674(92)90038-E . PMID 1547495 . S2CID 42832523 .
↑ Bradley, Desmond; Carpenter, Rosemary; Sommer, Hans; Hartley, Nigel; Coen, Enrico (1993). "Complementary floral homeotic phenotypes result from opposite orientations of a transposon at the plena locus of antirrhinum" . Cell . 72 (1): 85– 95. doi :10.1016/0092-8674(93)90052-R . PMID 8093684 . S2CID 23878779 .
↑ Coen, Enrico S.; Carpenter, Rosemary (1993). "The Metamorphosis of Flowers" . The Plant Cell . 5 (10): 1175– 1181. doi :10.2307/3869771 . JSTOR 3869771 . PMC 160351 . PMID 12271021 .
↑ Carpenter, R; Copsey, L; Vincent, C; Doyle, S; Magrath, R; Coen, E (1995). "Control of flower development and phyllotaxy by meristem identity genes in antirrhinum" . The Plant Cell . 7 (12): 2001– 2011. doi :10.1105/tpc.7.12.2001 . ISSN 1040-4651 . PMC 161057 . PMID 8718618 .
↑ Luo, Da; Carpenter, Rosemary; Vincent, Coral; Copsey, Lucy; Coen, Enrico (1996). "Origin of floral asymmetry in Antirrhinum" . Nature . 383 (6603): 794– 799. Bibcode :1996Natur.383..794L . doi :10.1038/383794a0 . ISSN 0028-0836 . PMID 8893002 . S2CID 2188470 .
↑ Da Luo; Carpenter, Rosemary; Copsey, Lucy; Vincent, Coral; Clark, Jennifer; Coen, Enrico (1999). "Control of Organ Asymmetry in Flowers of Antirrhinum" . Cell . 99 (4): 367– 376. doi :10.1016/s0092-8674(00)81523-8 . ISSN 0092-8674 . PMID 10571179 . S2CID 14346487 .
↑ Nath, Utpal; Crawford, Brian C. W.; Carpenter, Rosemary; Coen, Enrico (28 February 2003). "Genetic Control of Surface Curvature" . Science . 299 (5611): 1404– 1407. doi :10.1126/science.1079354 . PMID 12610308 . S2CID 8059321 .
↑ Corley, Susie B.; Carpenter, Rosemary; Copsey, Lucy; Coen, Enrico (5 April 2005). "Floral asymmetry involves an interplay between TCP and MYB transcription factors in Antirrhinum" . Proceedings of the National Academy of Sciences . 102 (14): 5068– 5073. Bibcode :2005PNAS..102.5068C . doi :10.1073/pnas.0501340102 . ISSN 0027-8424 . PMC 555980 . PMID 15790677 .
↑ Bradley, Desmond; Xu, Ping; Mohorianu, Irina-Ioana; Whibley, Annabel; Field, David; Tavares, Hugo; Couchman, Matthew; Copsey, Lucy; Carpenter, Rosemary; Li, Miaomiao; Li, Qun (17 November 2017). "Evolution of flower color pattern through selection on regulatory small RNAs" . Science . 358 (6365): 925– 928. Bibcode :2017Sci...358..925B . doi :10.1126/science.aao3526 . PMID 29146812 . S2CID 5060290 .
↑ Centre, John Innes. "How Snapdragons keep their colour: Signposting trick reveals evolutionary mechanism" . phys.org . Retrieved 25 September 2021 .