Ya-Sin switched his jersey number to 26 before the season, stating he wanted "a new beginning".[13] He was inactive against the Minnesota Vikings in week 2 due to a stomach illness.[14]
In Week 11 against the Green Bay Packers, Ya-Sin recorded his first interception of the season off a pass thrown by Aaron Rodgers during the 34–31 overtime win.[15]
Las Vegas Raiders
On March 16, 2022, Ya-Sin was traded to the Las Vegas Raiders in exchange for Yannick Ngakoue.[16] He played in 11 games with nine starts, recording 45 tackles and seven passes defensed.[17]
Baltimore Ravens
On May 3, 2023, Ya-Sin signed a one-year, $6 million contract with the Baltimore Ravens.[18] Ya-Sin made 14 appearances (including one start) for the Ravens, recording two pass deflections and 13 combined tackles.
San Francisco 49ers
On April 11, 2024, Ya-Sin signed a one-year contract with the San Francisco 49ers.[19] Ya-Sin made 13 appearances for San Francisco, compiling two pass deflections and three combined tackles.
Detroit Lions
On March 20, 2025, Ya-Sin signed with the Detroit Lions.[20] He played in all 17 games with six starts as the Lions third cornerback, recording 47 tackles and nine passes defensed.
On March 16, 2026, Ya-Sin re-signed with the Lions on a one-year, $4 million contract.[21]