Act 1

Scene 1:

At 9:30 pm, a pantomime unfolds between a small-time hustler Pez a lesson on pickpocketing to young vagrant Blazer. Soon, Reuben enters, a disheartened war veteran who reminisces about the good times in his life when he was part of a circus. Jane soon enters and asks Reuben for help in finding the BMT subway, however Reuben fails to speak and scares Jane away. Reuben commits himself to being able to speak and Fez soon returns, alarmed at Reuben's artificial demeanor, warning him that there are many thieves around. An Irish-American couple, Mr. and Mrs. J. Doakes, enter fighting which irritates Reuben, and soon Jane enters. They all hold a pleasant conversation and once Jane leaves the couple notice Reuben and soon exit. Reuben begins hating the world and decides to go for a drink.

Scene 2:

Place: The Bar

Time: 10:00 pm

Four "barflies" talk about their problems to the bar owner, Bart who is flipping coins anxiously as he's worried he'll lose power to his rival Malatesta. Soon, Reuben walks in which Bart takes as a sign from God. The two talk for a bit and Reuben gives Bart a note that says, "A high place." Bart's assistant Harry is tasked with helping Reuben find a place like this. Outside, Reuben passes two boys playing and sees one of the boy's shadow morph into a demon. He becomes fearful and states the words, "Bridge, that’s where." After his manic episode, he heads for the Manhattan Bridge. Harry is tasked to follow him while Bart places odds on his death with Malatesta while the "barflies" watch.

Scene 3:

Place: The Bridge

Time: 10:30 pm

The Italian-American woman Nina has just landed a job at a call center. To celebrate, she is lazily walking on the Manhattan Bridge but is 'rescued' by Reuben who thinks she is about to jump off. She interprets his advance as assault and a cop comes to rescue her. Realizing that Reuben was trying to save her, she poses as his girlfriend and shoos the cop away. As the couple walk away, the cop laments his treatment.

Scene 4:

Place: The Bar

Time: 11:00 pm

Bart begins to feel secure in his bet with Malatesta when Reuben and Nina enter. They talk about their new friendship and Nina invites Reuben to the San Gennaro festival in Little Italy, Manhattan. While Nina is in the bathroom, however, Bart encourages Reuben to commit suicide. Nina returns and senses Bart's malignant intentions. While they argue, Reuben escapes and is followed by Harry and Nina.

Scene 5:

Place: The Carnival

Time: 11:30 pm

Reuben and Nina are trying to find each other at the festival. However, Nina is being bothered by several friends and street vendors who are vying for her love. Once they find each other, the friends taunt the couple's love. Reuben entertains the crowd but Bart tries to get Reuben to talk about his father which the couple ignores, instead singing about love. Bart has Harry start a fight and Reuben tries to help but Nina gets him to leave.

Scene 6:

Place: The Column

Time: 12:30 pm

Reuben and Nina are sitting on a park bench together. Reuben, feeling remorseful, falls into a deep sleep on Nina's lap. When he wakes, they confess their love for each other. Soon, Bart's girlfriend appears and convinces them to come to the club "The Spot" where she works.

Scene 7:

Place: The Spot

Time: 1:00 am

The club is described by Blitzstein as a "tawdry, garish, sleazy, a Greenwich-village imitation of a fashionable night-club uptown." The Countess is performing a number when three girls perform a joint number after her. A fight between a black worker and a white patron upsets Reuben. The Countess eventually joins Nina, Reuben, and Bart at a table whereupon she tells the couple of Bart's bet. Reuben climbs to the chandelier and is encouraged to jump by Bart but dissuaded by Nina. Feeling unsure, when firefighters arrive with a net, he jumps and in the process reenacting his father's death.

Act 2

Scene 1:

Place: The Wards

Time: 2:30 am

After a brief intermezzo, it is revealed that Reuben and Nina have been placed in a mental institution. The couple each help someone from their side of the institution, and the couple is eventually released.

Scene 2:

Place: The Bedroom

Time: 3:00 am

Nina and Reuben return to Little Italy while Bart waits for them, the arranger of their release. Having conquered death, Reuben plans to go to a party at Bart's to face him.

Scene 3:

Place: The Bar

Time: 4:30 am

A large group has arrived at the bar and the couple quickly arrive. Bart insults Reuben and Reuben wants to hit him but restrains himself. Bart still thinks Reuben will kill himself but he sees an upside down horseshoe and pushes Reuben who pushes Bart back. The Countess tells them to just leave and Harry finally quits.

Scene 4:

Place: The Bridge

Time: Dawn

A shipman is returning to his boat in Brooklyn by taking the bridge. He meets the couple and waves them goodbye. Reuben and Nina vow to start again.