Mensah was born in Chiraa, Ghana, and comes from an academic family. He was born to parents from the Brong Ahafo Region,[2] and moved to Hertfordshire, England, with his father, Peter Osei Mensah,[3] an architect engineer, his mother, a writer, and two younger sisters at a young age. Mensah began practicing martial arts at the age of six.[4][5][6]
Though he had done drama in school, Mensah originally studied engineering, and arrived in Canada as an engineer for British Gas, developing gas fields at Morecambe Bay.
He voiced and provided his likeness for Sgt. Zach Hammond in EA's video game Dead Space.
Mensah played the character Oenomaus in Spartacus and was on the Spartacus Panel at Comic Con 2009 and 2011.[7] He had a recurring role in the fifth season of True Blood.