Between Coles Island and Salisbury, where Route 112 intersects the Trans-Canada Highway, Route 112 was a popular shortcut for travellers between the Fredericton and Moncton areas. In the Fredericton area, it was colloquially referred to as the "Coles Island Road". However, with the opening of the upgraded four-lane Trans-Canada Highway in 2001, Route 112's importance as a trans-provincial highway link has diminished. The road is not open to through truck traffic.