Mithridates had two sisters: Laodice III, the first wife of the Seleucid KingAntiochus III the Great, and Laodice of Pontus. He may have ruled in an uncertain period between 220 BC and 183 BC. Nothing is known of him since the years just cited, because the kingdom of Pontus disappears from history. His same existence is contested by certain historians, even if it is necessary to account for Appian's indication of Mithridates VI of Pontus as the eighth king of the dynasty and the sixth of the name.[1]