Kosmos 378 was the only DS-U2-IP satellite to be launched.[1][5] It was operated in an orbit with a perigee of 233 kilometres (145mi), an apogee of 1,697 kilometres (1,054mi), 74 degrees of inclination, and an orbital period of 104.4 minutes.[6] It completed operations on 13 September 1971,[7] before decaying from orbit and reentering the atmosphere on 17 August 1972.[6]
Payloads are separated by bullets ( · ), launches by pipes ( | ). Crewed flights are indicated in underline. Uncatalogued launch failures are listed in italics. Payloads deployed from other spacecraft are denoted in (brackets).