He played the 1982–83 season with HC Davos in Switzerland. He scored 49 goals and 32 assists. Although Davos was leading the season for more than 20 games, they ended in third place. In his next-to-last game for HC Davos, Kisio scored eight goals and two assists. The game's final score was 19–7.[2] Kisio left three days later for the Detroit Red Wings where he became a valuable player in the NHL.
Kisio's best season in the NHL was in 1992–93 with the San Jose Sharks. That season he tied a career high in goals (26) and points (78) and represented the Sharks in the 1993 NHL All-Star Game in Montreal after Pat Falloon went down with a season-ending shoulder injury.
Kisio ended his playing career with the Calgary Flames in 1995, who were ousted by his former team, San Jose in the playoffs. He then joined the Flames' scouting staff. For the 1998–99 season, he was named general manager of the Calgary Hitmen, who are owned by the Flames. With Kisio as GM, the Hitmen made the playoffs every year but one[1] (2010–11), won four regular season titles, and won the Western Hockey League title in both 1999 and 2010.
In the 2009 book 100 Ranger Greats, the authors ranked Kisio at No. 80 all-time of the 901 New York Rangers who had played during the team's first 82 seasons.[5]