SR203 begins at an intersection with SR15/SR121 in Blackshear, in Pierce County. The route heads northwest through rural areas until it enters Bacon County. It continues northwest until it has a very brief concurrency with SR32, east of Alma. SR203 curves to the east, and enters Appling County. There, it meets SR32 and SR121. Then, it continues to the east, entering Wayne County, to meet its northern terminus, an intersection with US84/SR38, southwest of Jesup.
SR203 is not part of the National Highway System, a system of roadways important to the nation's economy, defense, and mobility.[2]