Gene Tools, LLC is a limited liability company located in Philomath, Oregon, United States that manufactures Morpholinoantisenseoligos and delivery reagents.[1][2] Gene Tools was founded in 1997 and began regularly shipping custom-sequence Morpholino oligos in 2000. Current products include Morpholino oligos and Vivo-Morpholinos (for improved delivery into cells).
The manager and general partner, Jim Summerton, is a pioneer in antisense research,[3] conceived of and was co-inventor of the Morpholino antisense oligo structural type[4] and founded the first antisense therapeutics company, Sarepta Therapeutics Inc. (formerly AntiVirals Inc., renamed AVI BioPharma Inc., renamed Sarepta Therapeutics Inc.).
↑Morcos, PA (2001). "Achieving efficient delivery of morpholino oligos in cultured cells". Genesis. 30 (3): 94–102. doi:10.1002/gene.1039. PMID11477682.
↑Summerton, JE (May 1979). "Intracellular inactivation of specific nucleotide sequences: a general approach to the treatment of viral diseases and virally-mediated cancers". J. Theor. Biol. 78 (1): 77–99. Bibcode:1979JThBi..78...77S. doi:10.1016/0022-5193(79)90327-8. PMID114718.
