She joined the Cabinet Office as director of the Women's Unit in 1998.[3]
She became director general of the National Trust in 2001.[4][2] During her tenure, membership of the charity, which looks after 612,000 acres (2,480km2) of land in the United Kingdom, grew from 2.7 to 4million people. In February 2010 she was a guest on Private Passions, the biographical music discussion programme on BBC Radio 3.[5] Her appearance on the Chris Evans Breakfast Show on 18 February 2010 added momentum to the campaign to "save" Abbey Road studios.[6]
It was announced in March 2012 that Reynolds would be stepping down as director-general of the National Trust to become the next Master of Emmanuel College, Cambridge, in succession to Lord Wilson of Dinton.[3][7][8] She was admitted to her new post in October 2012, although was granted a leave of absence until October 2013.[citation needed]
In July 2020, the government announced that Reynolds had been appointed as the next chair of the National Audit Office (United Kingdom), a position she took up in January 2021.[9] She was succeeded as Master of Emmanuel College by Douglas Chalmers in October 2021.[10]
In January 2022 Reynolds became chair of governing council at the Royal Agricultural University in Cirencester, after having served as vice-chair since March 2021.[11] She remains in the position as of March 2026[update].[12]
She became a non-executive director of the BBC in January 2012[13] and Senior Independent Director in December 2012.[3] She also joined the board of Wessex Water as a non-executive director in August 2012.[14]
In 2019 she was awarded the Royal Geographical Society's Patron's Medal "for her contribution to environmental protection, conservation and the preservation of the British landscape".[21]
In July 2022, Reynolds received an Honorary Doctorate of Science from Royal Holloway, University of London, "for her achievements in the voluntary and public sectors, her leadership in higher education and her passionate advocacy for landscape, conservation and historical geography".[2]