Before serving as lieutenant governor, Keyes was a county supervisor and city councilman in his home city. He was affiliated with the Republican Party.[2] Keyes served as lieutenant governor under two governors, Harry Kelly from 1943 to 1945 and Kim Sigler from 1947 to 1949, both of whom were also Republicans.[4]
In 1965, two years after Keyes death, the clinic he founded was demolished to make way for parking lots.[3]
