CNOT2 Protein-coding gene in humans
CCR4-NOT transcription complex subunit 2 is a protein that in humans is encoded by the CNOT2 gene .[ 5] [ 6] It is a subunit of the CCR4-Not deadenylase complex.
References
1 2 3 GRCh38: Ensembl release 89: ENSG00000111596 – Ensembl , May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020166 – Ensembl , May 2017
↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ Albert TK, Lemaire M, van Berkum NL, Gentz R, Collart MA, Timmers HT (Mar 2000). "Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits" . Nucleic Acids Res . 28 (3): 809– 17. doi :10.1093/nar/28.3.809 . PMC 102560 . PMID 10637334 .
↑ "Entrez Gene: CNOT2 CCR4-NOT transcription complex, subunit 2" .
Further reading
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells" . Genome Res . 10 (10): 1546– 60. doi :10.1101/gr.140200 . PMC 310934 . PMID 11042152 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40– 5. doi :10.1038/ng1285 . PMID 14702039 .
Zwartjes CG, Jayne S, van den Berg DL, Timmers HT (2004). "Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex" . J. Biol. Chem . 279 (12): 10848– 54. doi :10.1074/jbc.M311747200 . PMID 14707134 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Shi J, Nelson MA (2005). "The cyclin-dependent kinase 11 interacts with NOT2". Biochem. Biophys. Res. Commun . 334 (4): 1310– 6. doi :10.1016/j.bbrc.2005.07.026 . PMID 16039607 .
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173– 8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55– 65. doi :10.1101/gr.4039406 . PMC 1356129 . PMID 16344560 .
Jayne S, Zwartjes CG, van Schaik FM, Timmers HT (2006). "Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex" . Biochem. J . 398 (3): 461– 7. doi :10.1042/BJ20060406 . PMC 1559471 . PMID 16712523 .