BET1 Protein-coding gene in the species Homo sapiens
BET1 homolog is a protein that in humans is encoded by the BET1 gene .[ 5] [ 6] [ 7]
This gene encodes a golgi-associated membrane protein that participates in vesicular transport from the endoplasmic reticulum (ER) to the Golgi complex . The encoded protein functions as a soluble N-ethylaleimide-sensitive factor attachment protein receptor and may be involved in the docking of ER-derived vesicles with the cis-Golgi membrane. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has not been determined.[ 7]
References
1 2 3 GRCh38: Ensembl release 89: ENSG00000105829 – Ensembl , May 20171 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032757 – Ensembl , May 2017↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ Zhang T, Wong SH, Tang BL, Xu Y, Peter F, Subramaniam VN, Hong W (Dec 1997). "The mammalian protein (rbet1) homologous to yeast Bet1p is primarily associated with the pre-Golgi intermediate compartment and is involved in vesicular transport from the endoplasmic reticulum to the Golgi apparatus" . J Cell Biol . 139 (5): 1157– 68. doi :10.1083/jcb.139.5.1157 . PMC 2140212 PMID 9382863 . ↑ Waters MG, Pfeffer SR (Nov 1999). "Membrane tethering in intracellular transport". Curr Opin Cell Biol . 11 (4): 453– 9. doi :10.1016/S0955-0674(99)80065-9 . PMID 10449330 . 1 2 "Entrez Gene: BET1 BET1 homolog (S. cerevisiae)" .
Further reading
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635– 48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173– 8. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7" . Nature . 424 (6945): 157– 64. Bibcode :2003Natur.424..157H . doi :10.1038/nature01782 PMID 12853948 . Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology" . Science . 300 (5620): 767– 72. Bibcode :2003Sci...300..767S . doi :10.1126/science.1083423 . PMC 2882961 PMID 12690205 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Zhang T, Hong W (2001). "Ykt6 forms a SNARE complex with syntaxin 5, GS28, and Bet1 and participates in a late stage in endoplasmic reticulum-Golgi transport" . J. Biol. Chem . 276 (29): 27480– 7. doi :10.1074/jbc.M102786200 PMID 11323436 . Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence" . Genome Res . 8 (11): 1097– 108. doi :10.1101/gr.8.11.1097 PMID 9847074 . Hay JC, Chao DS, Kuo CS, Scheller RH (1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells" . Cell . 89 (1): 149– 58. doi :10.1016/S0092-8674(00)80191-9 PMID 9094723 . S2CID 8682509 . Hay JC, Hirling H, Scheller RH (1996). "Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus" . J. Biol. Chem . 271 (10): 5671– 9. doi :10.1074/jbc.271.10.5671 PMID 8621431 .
