8-hidroksifuranokumarin 8-O-metiltransferase (EC2.1.1.70, furanokumarin 8-metiltransferase, furanokumarin 8-O-metil-transferase, ksantotoksol 8-O-metiltransferase, XMT, SAM:ksantotoksol O-metiltransferase, S-adenosil-L-metionin:8-hidroksifuranokumarin 8-O-metiltransferase, ksantotoksol metiltransferase, ksantotoksol O-metiltransferase, S-adenosil-L-metionin:ksantotoksol O-metiltransferase, S-adenosil-L-metionin-ksantotoksol O-metiltransferase) adalah sebuah enzim dengan nama sistematisS-adenosil-L-metionin:8-hidroksifurokumarin 8-O-metiltransferase.[1][2][3] Enzim ini mengkatalisisreaksi kimia umum berikut ini:
S-adenosil-L-metionin + sebuah 8-hidroksifurokumarin S-adenosil-L-homosistein + sebuah 8-metoksifurokumarin (reaksi umum)
Sebagai contoh, ksantotoksol diubah menjadi metoksasalen:[4][5]
[[File:No image file is associated with ksantotoksol via Wikidata. Try a qualifier ID or use chemrxn/subunit.|frameless|class=skin-invert-image|alt=2D representation of the chemical structure of ksantotoksol .]]
[[File:No image file is associated with metoksasalen via Wikidata. Try a qualifier ID or use chemrxn/subunit.|frameless|class=skin-invert-image|alt=2D representation of the chemical structure of metoksasalen .]]
↑Thompson HJ, Sharma SK, Brown SA (June 1978). "O-methyltransferases of furanocoumarin biosynthesis". Archives of Biochemistry and Biophysics. 188 (2): 272–81. doi:10.1016/s0003-9861(78)80009-5. PMID28084.
↑Hehmann M, Lukacin R, Ekiert H, Matern U (March 2004). "Furanocoumarin biosynthesis in Ammi majus L. Cloning of bergaptol O-methyltransferase". European Journal of Biochemistry. 271 (5): 932–40. doi:10.1111/j.1432-1033.2004.03995.x. PMID15009205.
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