Issue #0 was the first published in 1994. Psychopia was created by cartoonist/writer B. Patston. The fanzine evolved out of his small press comic Oy Mister!! published in 1992. Like Escape Magazine it printed comic strips.
Patston drew comics in his bedroom in Linslade typing up articles on his manual typewriter. He pasted up the final pages on his card table. The zine had a very downbeat amateurish look to it due to the underground sensibilities of the editor. The misspelling Psycopia for the magazine originated with the reputation for text mangling, technical typesetting failures and typographical errors, and once misspelled its own name on the cover as "Psycopia".