Pallor is more evident on the face and palms. It can develop suddenly or gradually, depending on the cause. It is not usually clinically significant unless it is accompanied by a general pallor (pale lips, tongue, palms, mouth and other regions with mucous membranes). It is distinguished from similar presentations such as hypopigmentation (lack or loss of skin pigment) or simply a lightly-melanated complexion.
In patients with dark skin, pallor is more subtle and harder to detect, often manifesting as a more grayish or ashy tone of skin in individuals with very dark brown skin, or alternatively a more yellowish tone in individuals with lighter brown skin. Assessing the palms, soles, and mucous membranes with appropriate lighting in such cases may make detection easier.[1][2]
↑Drummond, Peter D. (October 1997). "Correlates of facial flushing and pallor in anger-provoking situations". Personality and Individual Differences. 23 (4): 575–582. doi:10.1016/S0191-8869(97)00077-9.
↑Poterucha, Joseph T.; Bos, J. Martijn; Cannon, Bryan C.; Ackerman, Michael J. (1 August 2015). "Frequency and severity of hypoglycemia in children with beta-blocker–treated long QT syndrome". Heart Rhythm. 12 (8): 1815–1819. doi:10.1016/j.hrthm.2015.04.034. ISSN1547-5271. PMID25929701.