At the age of seven, Ma Sichun began her acting career with a role in The Winter of Three Persons; and in 2001, she starred in The Grand Mansion Gate, both alongside her aunt Jiang Wenli.[5]
Ma became well known after serving as the cover model for Rao Xueman's novel Joy & Sorrow. She starred as a lead in the series Lover, based on the novel Daddy, I have your baby, director by Shen Yan.[6] In 2012, Ma won the Golden Phoenix Awards for Best Newcomer for her performance in the film Time Flies Soundlessly.[7]
In 2021, Ma starred as a doctor in the military-medical romance drama You Are My Hero alongside Bai Jingting,[23] which ranked 1st and gained over 1.35B views on Tencent.[24] Later, she starred in youth drama film Wild Grass.[25]
《烟火人家》今晚央一首播，徐帆、马思纯首演母女，诠释家人温情 ！["Fireworks Family" will be broadcast tonight on CCTV1. Xu Fan and Ma Sichun make their mother-daughter debut, interpreting the warmth of family!]. CCTV News (in Chinese). February 13, 2024. Archived from the original on March 2, 2024. Retrieved March 2, 2024.*HOME, CPOP (2024-02-16). "Islands - Xu Fan, Ma Sichun". CPOP HOME. Retrieved 2025-11-19.
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