Born Daniel Salvator Duva in Paterson, New Jersey, he was a son of prominent boxing trainer Lou Duva. He gained a law degree in 1977. When Leon Spinks' manager came for help in 1978, Duva gladly helped him. With earnings of $500,000 ($2.5 million today), Duva formed Main Events in April 1978, together with his father and his brother Dino Duva. He married Kathy Duva, the current Main Events CEO. He was one of the earliest promoters to achieve financial success in the pay-per-view market. He first gained prominence in the boxing world through the 1981 promotion of the Sugar Ray Leonard vs. Thomas Hearns welterweight championship fight, which grossed $40 million ($140 million today) in pay-per-view and closed circuit revenue.
After the 1984 Olympics, Duva successfully signed many of the competitors there, which helped to establish Main Events as a premier promoter.